3,4-二咖啡酰奎宁酸(异绿原酸 B)
3,4-二咖啡酰奎宁酸((1S,3R,4R,5R)-3,4-Bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-1,5-dihydroxycyclohexane-1-carboxylic acid)
CAS: 14534-61-3
化学式: C25H24O12
| 中文名 | 3,4-二咖啡酰奎宁酸 |
| 英文名 | (1S,3R,4R,5R)-3,4-Bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-1,5-dihydroxycyclohexane-1-carboxylic acid |
| 别名 | 异绿原酸B 异绿原酸B(3 二咖啡酰奎宁酸 3,4-二咖啡酰奎宁酸 异绿原酸B(3,4-二咖啡酰奎宁酸) 3,4-二咖啡酰奎宁酸(异绿原酸 B) ISOCHLOROGENIC ACID B 异绿原酸B ISOCHLOROGENIC ACID B 异绿原酸B 标准品 |
| 英文别名 | Isochlorogenic acid B ISOCHLOROGENIC ACID B(RG) 3,4-Dicaffeoylquinic acid Isochlorogenic acid B, froM Lonicera japonica Isochlorogenic acid B,3,4-Dicaffeoylquinic acid 1β,3β-Dihydroxy-4β,5α-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1α-cyclohexanecarboxylic acid (1S)-4β,5α-Bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β,3β-dihydroxycyclohexanecarboxylic acid (1R,4R,5R)-3,4-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,5-dihydroxycyclohexanecarboxylic acid (1S)-1α,5α-Dihydroxy-3β,4α-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]oxy]-1β-cyclohexanecarboxylic acid (1S,3R,4R,5R)-3,4-bis{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,5-dihydroxycyclohexanecarboxylic acid (1S,3R,4R,5R)-3,4-Bis[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy]-1,5-dihydroxycyclohexane-1-carboxylic acid |
| CAS | 14534-61-3 |
| 化学式 | C25H24O12 |
| 分子量 | 516.45 |
| InChI | InChI=1/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(35,24(33)34)11-19(30)23(20)37-22(32)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-30,35H,11-12H2,(H,33,34)/b7-3+,8-4+/t19-,20?,23-,25-/m1/s1 |
| 密度 | 1?+-.0.1 g/cm3(Predicted) |
| 熔点 | >117°C (sub.) |
| 沸点 | 810.8±65.0 °C(Predicted) |
| 比旋光度 | -225 (MeOH) |
| 闪点 | 274.9°C |
| 蒸汽压 | 8.9E-28mmHg at 25°C |
| 溶解度 | 甲醇 (微溶) |
| 折射率 | 1.719 |
| 酸度系数 | 3.70±0.50(Predicted) |
| 存储条件 | Sealed in dry,Store in freezer, under -20°C |
| 外观 | 固体 |
| 颜色 | Off-White to Light Yellow |
| 物化性质 | 类色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于金银花，忍冬，杜仲。 |
| MDL号 | MFCD22375481 |
| 体外研究 | 3,4-Dicaffeoylquinic acid acts as a greater primary antioxidant than its methanol extract, by having higher ferric reducing activity (EC 50 2.18 μg/ml), β-carotene bleaching activity (EC 50 23.85 μg/ml) and DPPH scavenging activity (EC 50 68.91 μg/ml). 3,4-Dicaffeoylquinic acid exhibits a remarkable dose-dependent inhibitory effect on NCI-H23 (human lung adenocarcinoma) cell lines (EC 50 3.26 μg/ml) and is found to be apoptotic in nature based on a clear indication of DNA fragmentation. 3,4-Dicaffeoylquinic acid also displays a concentration-dependent α-glucosidase inhibition with EC 50 241.80 μg/ml. |
| 安全术语 | 24/25 - 避免与皮肤和眼睛接触。 |
| WGK Germany | 3 |
| 海关编号 | 29189900 |
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3,4-二咖啡酰奎宁酸(异绿原酸 B) - 简介
3,4-二咖啡酰奎宁酸（3,4-dicaffeoylquinic acid）是一种化学物质，属于多酚类化合物。下面是关于它的性质、用途、制法和安全信息的介绍：
性质：
- 外观：呈黄色结晶粉末
- 溶解性：在水中溶解度较低，易溶于乙醇和醚类溶剂
- 稳定性：在中性和弱酸性条件下相对稳定，但在强酸性和碱性条件下会分解
用途：
- 天然产物：3,4-二咖啡酰奎宁酸被发现广泛存在于多种植物中，如菊花、艾草、牡丹等。
- 药理作用：研究表明，3,4-二咖啡酰奎宁酸具有抗糖尿病、抗癌、抗心血管疾病等多种药理作用。它可以抑制炎症反应、减少氧化应激并保护细胞免受损害。
制法：
3,4-二咖啡酰奎宁酸可以通过提取自含有该化合物的植物材料，然后进行纯化和结晶得到。另外，也可以通过化学合成方法合成得到。
安全信息：
3,4-二咖啡酰奎宁酸是一种天然物质，相对较安全。但对于过敏体质的人群应谨慎使用，因为可能引起过敏反应。在使用时应遵循适当的剂量，避免长期大剂量使用。
性质：
- 外观：呈黄色结晶粉末
- 溶解性：在水中溶解度较低，易溶于乙醇和醚类溶剂
- 稳定性：在中性和弱酸性条件下相对稳定，但在强酸性和碱性条件下会分解
用途：
- 天然产物：3,4-二咖啡酰奎宁酸被发现广泛存在于多种植物中，如菊花、艾草、牡丹等。
- 药理作用：研究表明，3,4-二咖啡酰奎宁酸具有抗糖尿病、抗癌、抗心血管疾病等多种药理作用。它可以抑制炎症反应、减少氧化应激并保护细胞免受损害。
制法：
3,4-二咖啡酰奎宁酸可以通过提取自含有该化合物的植物材料，然后进行纯化和结晶得到。另外，也可以通过化学合成方法合成得到。
安全信息：
3,4-二咖啡酰奎宁酸是一种天然物质，相对较安全。但对于过敏体质的人群应谨慎使用，因为可能引起过敏反应。在使用时应遵循适当的剂量，避免长期大剂量使用。
最后更新：2024-04-09 20:52:54
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提供多种规格现货供应
产品名: 异绿原酸B(10mM in DMSO,无菌) 去供应商网站查看 询盘CAS: ID02401
产地: 北京
包装: 1ml/瓶
规格: ID02401-1ml
价格: 电话、微信、QQ、邮件
库存: 现询
电话: 010-50973130
手机: 17801761073(微信同号)
电子邮件: 3193328036@qq.com
QQ: 3193328036
微信: 17801761073
产品描述: 索莱宝直销,欢迎来询
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